What are the best tests for health and longevity? What are the best tests to track your health, prevent diseases, and reach your optimal lifespan potential? The science of optimal health, preventive medicine and longevity is moving fast. This is one reason why...
Why Testosterone Therapy Accelerates Aging
If you are male and an anti-aging doctor or guru recommends taking testosterone for longevity: run. There are two main reasons why to run away: or this person is not up to date with insights into aging of the last 30 years, or they just want you to sell to you...
Best Health Supplements According To Science
HEALTH SUPPLEMENTS (VS LONGEVITY SUPPLEMENTS) We earlier discussed the importance of distinguishing between “health supplements” and “longevity supplements”: Longevity supplements (or “anti-aging” supplements) specifically slow down aging and extend lifespan, ideally...
What Can We Do to Slow Aging and Live Longer?
There has never been a better time to live longer and healthier than today. In the past two decades, we learned more about aging and health than in the two thousand years prior (read about the "main causes of aging" here). However, we are currently being...
Does Rapamycin Cause High Glucose, Lipids and Diabetes?
Rapamycin (sirolimus) is one of the most promising anti-aging drugs around. Various studies show rapamycin can extend lifespan (learn more here). However, some people are concerned about potential negative side effects of rapamycin, such as immunosuppression (I...
How Does Rapamycin Work? Overview of Rapamycin Lifespan Extension Studies
Rapamycin is one of the most promising drugs to extend lifespan and slow aging. In nearly all studies, rapamycin extends lifespan; see below an overview of studies. Contrary to many other lifespan extending drugs, rapamycin extends lifespan in both males and females...
Does Rapamycin Increase Infection Risk?
Rapamycin (also called sirolimus) is one of the most well-known, researched, and promising drugs for anti-aging and longevity. According to various experts, including Professor Matt Kaeberlein, it’s currently the best drug we have for longevity, significantly...
Other Reasons Why We Age
I listed some major reasons why we age, such as DNA damage, epigenetic changes and mitochondrial dysfunction. Of course, there are other reasons why we grow old, and various others will be discovered. Below are a few examples of other potential causes of...
Causes of Aging: Deregulated Nutrient Sensing
As we get older, our bodies, and our cells specifically, become less able to deal with the nutrients we consume. Most of us eat three meals per day, leading to a lot of sugars (including from starches), amino acids (from proteins) and fats entering our...
Causes of Aging: Altered Intercellular Communication
Cells communicate with each other in many ways. Cells continuously secrete thousands of different substances such as metabolites, DNA, RNA, proteins, peptides, hormones, neurotransmitters, vesicles, and lots of other things, reaching other cells, impacting...