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HEALTH SUPPLEMENTS (VS LONGEVITY SUPPLEMENTS) We earlier discussed the importance of distinguishing between “health supplements” and “longevity supplements”: Longevity supplements (or “anti-aging” supplements) specifically slow down aging and extend lifespan, ideally...
There has never been a better time to live longer and healthier than today. In the past two decades, we learned more about aging and health than in the two thousand years prior (read about the "main causes of aging" here). However, we are currently being...
Rapamycin (sirolimus) is one of the most promising anti-aging drugs around. Various studies show rapamycin can extend lifespan (learn more here). However, some people are concerned about potential negative side effects of rapamycin, such as immunosuppression (I...
Rapamycin is one of the most promising drugs to extend lifespan and slow aging. In nearly all studies, rapamycin extends lifespan; see below an overview of studies. Contrary to many other lifespan extending drugs, rapamycin extends lifespan in both males and females...
Rapamycin (also called sirolimus) is one of the most well-known, researched, and promising drugs for anti-aging and longevity. According to various experts, including Professor Matt Kaeberlein, it’s currently the best drug we have for longevity, significantly...
I listed some major reasons why we age, such as DNA damage, epigenetic changes and mitochondrial dysfunction. Of course, there are other reasons why we grow old, and various others will be discovered. Below are a few examples of other potential causes of...
As we get older, our bodies, and our cells specifically, become less able to deal with the nutrients we consume. Most of us eat three meals per day, leading to a lot of sugars (including from starches), amino acids (from proteins) and fats entering our...
Cells communicate with each other in many ways. Cells continuously secrete thousands of different substances such as metabolites, DNA, RNA, proteins, peptides, hormones, neurotransmitters, vesicles, and lots of other things, reaching other cells, impacting...
Every second your body produces 2.5 million red blood cells. Which means that each day your body produces around 200 billion red blood cells. On top of that, your body creates billions of white blood cells and around 400 billion platelets per day (platelets...
As we age, senescent cells arise everywhere in our body. Senescent cells are cells that are damaged but refuse to die. Despite their damage, and their malfunctioning, they keep lingering on. Some scientists call them “zombie” cells, because they normally should...
During aging, our tissues become crosslinked. Crosslinks are connections (“links”) formed between the building blocks that make up our tissues. For example, sugar molecules are able to form crosslinks between proteins like collagen, which is an important...
Telomeres are the “caps” on our DNA which protect our DNA. Just like shoestrings have plastic caps to protect them from unraveling, our DNA strands have telomeres that protect them against unraveling. Telomeres are made of DNA themselves. But this DNA does not...
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