I listed some major reasons why we age, such as DNA damage, epigenetic changes and mitochondrial dysfunction. Of course, there are other reasons why we grow old, and various others will be discovered. Below are a few examples of other potential causes of...
Causes of Aging: Deregulated Nutrient Sensing
As we get older, our bodies, and our cells specifically, become less able to deal with the nutrients we consume. Most of us eat three meals per day, leading to a lot of sugars (including from starches), amino acids (from proteins) and fats entering our...
Causes of Aging: Altered Intercellular Communication
Cells communicate with each other in many ways. Cells continuously secrete thousands of different substances such as metabolites, DNA, RNA, proteins, peptides, hormones, neurotransmitters, vesicles, and lots of other things, reaching other cells, impacting...
Causes of Aging: Stem Cell Exhaustion
Every second your body produces 2.5 million red blood cells. Which means that each day your body produces around 200 billion red blood cells. On top of that, your body creates billions of white blood cells and around 400 billion platelets per day (platelets...
Causes of Aging: Senescent Cells
As we age, senescent cells arise everywhere in our body. Senescent cells are cells that are damaged but refuse to die. Despite their damage, and their malfunctioning, they keep lingering on. Some scientists call them “zombie” cells, because they normally should...
Causes of Aging: Advanced Glycation End Products (AGEs)
During aging, our tissues become crosslinked. Crosslinks are connections (“links”) formed between the building blocks that make up our tissues. For example, sugar molecules are able to form crosslinks between proteins like collagen, which is an important component...
Causes of Aging: Telomere Shortening
Telomeres are the “caps” on our DNA which protect our DNA. Just like shoestrings have plastic caps to protect them from unraveling, our DNA strands have telomeres that protect them against unraveling. Telomeres are made of DNA themselves. But this DNA does not...
My Science-Based Anti-Aging Skin Care Routine
What’s the best skin care routine to reduce wrinkles and look younger? For most people, it’s difficult to find a proper answer to that question. Lot's of skin care advice is of low quality. Some important reasons for this are the following: 1. Lot's of (online)...
How Will Biotechnology Transform Our Health and Lifespan?
Likely, the biggest breakthrough in medicine of all time will be the reversal of the aging process. The reasons for this are logical and obvious, but are still all too little known, even by the medical community and in the field of biotechnology and pharma....
Causes of Aging: Mitochondrial Dysfunction
The mitochondria are the powerplants of our cells. They generate the energy cells need to function. The reason why we eat food and breathe oxygen is to mainly keep our mitochondria going. The sugars, fats and amino acids from our food, and the oxygen we...