Longevity
Causes of Aging: Senescent Cells

Causes of Aging: Senescent Cells

  As we age, senescent cells arise everywhere in our body. Senescent cells are cells that are damaged but refuse to die. Despite their damage, and their malfunctioning, they keep lingering on. Some scientists call them “zombie” cells, because they normally should...

Causes of Aging: Telomere Shortening

Causes of Aging: Telomere Shortening

  Telomeres are the “caps” on our DNA which protect our DNA. Just like shoestrings have plastic caps to protect them from unraveling, our DNA strands have telomeres that protect them against unraveling. Telomeres are made of DNA themselves. But this DNA does not...

Causes of Aging: Genomic Instability

Causes of Aging: Genomic Instability

  DNA contains the instructions to build our cells, and so our body. Consider the DNA as an instruction manual for how to build a human. DNA contains the code for making thousands of different proteins, which build up our cells and carry out most of the functions...

Causes of Aging: Loss of Proteostasis

Causes of Aging: Loss of Proteostasis

  Each cell in our body contains millions of proteins. Proteins are the building blocks of our cells. Proteins are also the working horses given they carry out most of the functions in our cells. For example, there are proteins that form channels (gates) in the...